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Clinical Guidelines

Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Living Guideline for the Management of Axial Spondyloarthritis

April 22, 2026

The management of axial spondyloarthritis (axSpA) is a complex and rapidly changing field for Canadian rheumatologists. The Spondyloarthritis Research Consortium of Canada (SPARCC) and the Canadian Rheumatology Association (CRA) last updated treatment recommendations for the management of axSpA in 2014(1,2). The axSpA treatment landscape has changed significantly in the interim, and now includes new classes of biologic disease-modifying anti-rheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs) with unique risks and benefits...