2015 Grant Awards
The posters and papers listed below each grant arise from work facilitated through the grant funding.
Preventing rheumatoid arthritis (Pre-RA): Perspectives of people at risk and of rheumatologists on selected interventions
Principal Investigator: Harrison, M; Hudson, M. (PDF)
Co-investigators: Bansback, N; Koehn, C
Project Summary
Increasingly, evidence suggests that treatment of people at risk of rheumatoid arthritis (RA) with anti-rheumatic drugs could prevent the onset of disease, and there are ongoing trials evaluating the effectiveness of different treatments in preventing RA. A preventative treatment would come with considerable uncertain risks and benefits in practice. Using choice experiments, this project aims is to understand the level of evidence, potential risks, benefits and features a preventative treatment strategy would need to offer to be acceptable to people at risk of developing RA and for rheumatologists.
Oral Presentations
- Vancouver Health Economics Meeting, June 2016, “Is there evidence for concordance between patient and physicians for aspects of treatments that matter most? Evidence from a review of Discrete Choice Experiments” Harrison, M; Milbers, K; Hudson, M; Bansback, N.
- International Health Economics Association – Boston, July 2017, “Preventing rheumatoid arthritis: general population perspectives on the risk developing the disease and on potential preventative interventions in a pilot study,” Harrison M, Bansback N, Spooner L, Milbers K, Koehn C, Hudson M.
- American College of Rheumatology, San Diego, November 2017, “Preventing Rheumatoid Arthritis: North American Perspectives of Patients and First-Degree Relatives on the Risk of Developing the Disease and of Potential Preventative Interventions” Harrison M, Spooner L, Hudson M, Koehn C, Finckh A, Bansback N.
- American College of Rheumatology, Chicago October 2018, “Patient-Physician Communication about Medication Costs in Rheumatoid Arthritis” Kaal KJ, Bansback N, Anis A, Harrison MJ.
- University of Oxford, Oxford, January 2018, “Preventive treatment for rheumatoid arthritis: are we looking in the right direction?” Harrison M.
- Canadian Rheumatology Association Annual Scientific Meeting, Vancouver, February 2018, “Preventing Rheumatoid Arthritis (Pre-RA): Preferences of Potential Recipients, Patients, and Health Care Professionals for Preventative Treatment” Harrison M, Bansback N, Spooner L, Koehn C, Hudson M.
Poster Presentations
Presented at the 2016 Society for Medical Decision Making (SMDM) North American Meeting.
Presented at the 2017 Canadian Rheumatology Association meeting.
Presented at the 2017 Canadian Association of Health Services and Policy Research (CAHSPR) Conference
Presented at the 2017 European League Against Rheumatism (EULAR)
- Preventing rheumatoid arthritis: a general population pilot study on perspectives of the risk of developing the disease and potential preventative treatment (PDF)
- Perspectives of Patients, First Degree Relatives, and Rheumatologists Around Preventative Treatments for Rheumatoid Arthritis (PDF)
Presented at the 2017 Society for Medical Decision Making Meeting
Presented at the 2018 Canadian Agency for Drugs and Technologies in Health (CADTH) Symposium
Presented at the 2019 Canadian Rheumatology Association meeting.
Published Literature
- Harrison M, Milbers K, Hudson M, et al; Do patients and health care providers have discordant preferences about which aspects of treatments matter most? Evidence from a systematic review of discrete choice experiments; BMJ Open (2017)
- Munro S, Spooner L, Milbers K, Hudson M, Koehn C, Harrison M. Perspectives of patients, first-degree relatives and rheumatologists on preventive treatments for rheumatoid arthritis: A Qualitative Analysis. BMC Rheumatology. 2018 2:18
- Harrison M, Spooner L, Bansback N, Milbers K, Koehn C, Shojania K, Finckh A, Hudson M. Preventing Rheumatoid Arthritis: Preferences for and Predicted Uptake of Preventive Treatments for Rheumatoid Arthritis Among High Risk Individuals. PLoS One. Accepted April 2019
- Harrison M, Bansback N, Aguiar M, Koehn C, Shojania K, Finckh A, Hudson M, Preferences for treatments to prevent rheumatoid arthritis in Canada and the influence of shared decision-making, Clinical Rheumatology, Accepted March 2020